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    Live better, longer.

    The most scientifically advanced formulas designed to restore your NAD+levels and optimize your potential for healthy longevity.

Live better, longer.

The most scientifically advanced formulas designed to restore your NAD+levels and optimize your potential for healthy longevity.

What is NMN?

NMN (nicotinamide mononucleotide) is a naturally occurring molecule found in living cells. It is a direct precursor your body can use to make NAD+(nicotinamide adenine dinucleotide), a coenzyme that powers cellular energy metabolism and day-to-day maintenance. When NAD+is in short supply, cells may struggle to keep up with everyday demands. NAD+naturally declines by about 1% every year, so even with a healthy diet and active lifestyle, NAD+might not keep up with daily demands.

You can't live without NAD+.

The bad news: NAD+ levels are destroyed by aging, inflammation, diet, stress, and sickness. This leads to weakness, frailty, and even faster aging.


The good news: You can help restore your NAD+ levels with exercise, nutrition, and targeted supplement formulas.

NAD+ precursor response is personal.

The enzymes that rebuild your NAD+ stores vary by person and tissue, so the same supplement doesn’t always produce the same effect.


Supporting multiple pathways with NMN, NR, and Trigonelline helps you get reliable, steady NAD+ support without guesswork.

NAD+ boosters like NMN and NR are only the beginning.

After years of analyzing the research, we've aligned with a systems-level approach to address four main pathways to support healthy NAD+levels throughout the entire body. This systems-level approach is described elegantly by Nichola Conlon and Dianne Ford in a recent study on NAD+ restoration.

Every Renue By Science formula helps you maximize NAD+through one of these pathways.

Boost

Protect

Optimize

Regenerate

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Liposomal delivery means greater bioavailability.

Liposomal delivery wraps sensitive ingredients like NMN and NR in phospholipids, the same fats that make up cell membranes, so they’re protected during digestion and first-pass liver processing.


This translates to more of the active ingredients reaching your cells where you need them most, and more powerful effects at significantly lower doses.

Our Team

  • Bryan Nettles

    Founder and CEO

    Nutrition and exercise have been a primary focus for me throughout my life. My passion is in science and research, especially as it relates to healthy aging.

  • Dr. Rebecca Crews

    Research Director

    Dr. Rebecca Crews is the Research Director at Renue by Science, leading the company’s engagement in transformative research.

  • Dr. Clark Driggers

    Chief Medical Advisor

    Dr. Clark Driggers, serves as the Chief Medical Advisor at Renue By Science, specializing in wellness, anti-aging, and regenerative medicine.

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      NMN Product Comparison

    Convenience/Portability

    This is ideal for those who want the ability to take NMN with them throughout the day. Our sublingual tablets, LIPO capsules, and nasal spray are ideal for those who are on the go and who like to take NMN at different intervals throughout the day.

    Fast Acting

    If fast acting is important to you, then we recommend our sublingual powder, tablets, or nasal spray as they bypass digestion. They can provide rapid absorption and reach systemic circulation for a noticable effect in minutes. So whether it’s before a quick workout or you need to quickly focus on mental tasks, these products can give you a quick boost when you need it most.

    Long Lasting

    LIPO NMN lasts longer in the body than our other NMN products. Liposomes protect the active ingredients from digestion and release slowly in the bloodstream up to 24 hours.

    Fastest Cognitive Effect

    The sublingual powder has a very fast effect on physical energy, but the intranasal spray has a much stronger impact on improved cognition (the relief of “brain fog”).

    Improved Energy

    Sublingual delivery is much faster acting and the energy boost is more quickly noticed, but the most common report from users of allNAD+boosters is increased energy.

    Easiest to Take

    Some people have trouble swallowing pills or applying powder under the tongue. For those people, LSG NMN is easier because it comes in an easy to apply liquid gel.

    Best Bioavailability

    Approximately 30% of NMN taken sublingually gets absorbed directly into the bloodstream, while the rest passes through the GI tract and gets broken down into less effective nicotinamide. However liposomal delivery avoids degradation in the GI tract entirely, meaning far more NMN is delivered to the tissues intact.

    Best Cost per Milligram

    The NMN product with the best price is our sublingual powder as there is very little added cost for processing. Tablets are next. Manufacturing of Liposomes takes the most time and expensive machinery, so cost the most per Milligram.

    Best Overall Value

    The best overall value is the product which is best in price combined with best bioavailability. Bioavailability is how much of the product actually makes it to the cells intact. For example, our LIPO capsules cost more per milligram to manufacture, but are 3 to 5 times more bioavailable than sublingual products, so are much more cost effective.

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    Customer reviews

     
     

    FAQs

    What is Pure NMN Powder and how does it work?

    Answer: Pure NMN Powder contains nicotinamide mononucleotide (NMN), a direct precursor to the vital coenzyme NAD+, which plays a key role in cellular energy metabolism and DNA repair. By supplementing with NMN, you help support your body’s natural NAD+ production, which tends to decline with age.

    How should I take this product?

    Answer: This powder can be taken daily, with flexible dosing adjusted to your goals. Many people start with a smaller amount and adjust based on tolerance and experience. Some users prefer sublingual absorption (holding under the tongue before swallowing) for potentially improved uptake. Always consult a healthcare provider for personalized guidance.

    Is this NMN Powder tested for quality and purity?

    Answer: Yes. The Pure NMN Powder is pharmaceutical-grade and undergoes multiple rounds of rigorous testing in certified labs to ensure high quality, potency, and purity — with independent verification such as COA (Certificate of Analysis) available.

    Who should consult a doctor before using this supplement?

    Answer: While NMN is generally well-tolerated, people who are pregnant or nursing, have pre-existing medical conditions, or are taking prescription medications should consult a healthcare provider before starting this supplement.